North Carolina's defense lost one reserve, defensive tackle Greg Elleby, for the season and is still without linebacker Quan Sturdivant.
Elleby, a senior, who has been an all-purpose reserve for the Tar Heels, tore the ACL and MCL in his left knee in the second half of UNC's 42-17 win over East Carolina on Saturday and is out for the season.
Sturdivant injured his left hamstring against Rutgers on Sept. 25 and did not play against ECU. UNC coach Butch Davis said Sturdivant was getting better but they would not know if he could play against Clemson until later this week.
Sturdivant leads UNC with 27 tackles in three games.
Elleby played both sides of the ball in the past two seasons, switching from defensive tackle to center in the middle of the 2009 season when injuries decimated the Heels' offensive line. With Robert Quinn, Marvin Austin and Michael McAdoo out of the lineup because of the NCAA investigation, UNC's depth on the defensive front has been limited.
Elleby switched back to defensive tackle after the LSU game and was a reserve behind Quinton Coples and Tydreke Powell.