One of 2014’s biggest hits at the box office, Christopher Nolan’s “Interstellar,” has drawn comparisons to many classic movies from the genre of cerebral sci-fi, but none more than Stanley Kubrick’s 1967 cinematic milestone “2001: A Space Odyssey,” which screens Wednesday night at the Colony Theater in Raleigh. Described in its original promotion as “an epic drama of adventure and exploration,” the film is an adaptation of the best-selling novel by Arthur C. Clarke, who collaborated with Kubrick on the screenplay. For the uninitiated, Keir Dullea and Gary Lockwood star as astronauts on a mysterious mission to Jupiter that may be jeopardized by their ship’s seemingly sentient computer, HAL 9000. From its iconic “Dawn of Man” opening depicting primitive man-apes reacting to a large shiny black monolith, to its psychedelic “Beyond the Infinite” closing sequence, “2001” is a mind-bending must-see on the big screen. And it’s way better than “Interstellar,” too. It starts at 7:30, and admission is $5. Details: 919-847-5677 or ambassadorcinemas.com.