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A kidney renews a friend's life

- Staff Writer

Published: Sat, Oct. 11, 2008 12:30AM

Modified Sat, Oct. 11, 2008 04:13AM

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An instant bond of friendship formed between Lori Christian and Marie Molin when they met through their children eight years ago.

Molin taught Christian's youngest child in preschool and kindergarten, and the two women had one of those small-world ties where other family members had known each other for years.

But as tight as they had grown, Christian and Molin are even more connected now. Last week, Molin donated one of her kidneys to Christian, who was quietly dying from a degenerative kidney disease.

ORGAN DONATION

There are 3,003 people on the organ donation waiting list in the region of North Carolina that includes the Triangle. Of those, 2,329 need kidneys, including 1,394 African-Americans.

* Living donation was first done in 1954, taking a kidney from one identical twin and transplanting it to the other. By 2001, living donations became the predominant kidney transplant source.

* Organs from a living donor improve a recipient's survival; less time spent on the waiting list means less time on dialysis, which makes for a healthier patient.

* Transplants are more successful when organs are matched between members of the same racial and ethnic groups, which have greater genetic similarities.

* To be a donor, make your wishes known on your driver's license, and to family members.

AMERICAN SOCIETY OF NEPHROLOGY, THE ORGAN PROCUREMENT AND TRANSPLANTATION NETWORK

"I don't know how I can repay her," Christian, 47, said from her bed at Duke Hospital. "The fact is, this will give me a quality of life I never thought I could have."

The act of generosity, while not rare, is uncommon, given the need for kidneys and other organs. And among African-Americans, the need is even more acute. Because kidney disease is three times more prevalent among blacks than whites -- a result, often, of higher rates of contributing causes such as diabetes and hypertension -- the demand is especially high for organs from live donors, as well as victims of tragedy.

African-Americans represent 13 percent of the U.S. population, but comprise 23 percent of people waiting on kidney donor lists, according to the U.S. Department of Health and Human Services.

Christian was one of those on the waiting list, both at Duke and at nearby UNC Hospitals. Had it not been for Molin offering one of her organs, said Duke transplant surgeon Dr. Paul C. Kuo, Christian might have waited two to five years for a kidney. All the while, she'd have grown sicker and sicker -- and could have died.

"This is one of the most satisfying things we do as transplant surgeons," Kuo said. "It's a cure in the short term."

Few knew that Lori Christian was sick. She felt fine until returning from a vacation in Mexico six years ago with weird swelling in her legs. She initially chalked it up to a bug she might have picked up, but tests showed she had focal segmental glomerulosclerosis, a progressive kidney disease that affects the body's ability to process toxins.

It's the same disease that struck NBA star Alonzo Mourning in 2003. The cause is unknown.

For a while, Christian did well. She was able to continue playing tennis, plus keep up with her children's busy soccer and baseball schedules. But a regimen of steroids, which helps some people who have the disease, did little for her other than cause rapid weight gain. By last October, she was losing energy and would come home from work as a Wake District Court judge exhausted, unable to fully participate in her family's bustling activities.

"I would just come home and go to bed," she said. With her kidneys failing, she began dialysis in December. Her husband, Wayne, learned to operate a home dialysis machine -- a big, noisy contraption that required knocking a hole in their bedroom wall to reach water pipes for the filtration system. For four hours every other day, artificial filtration kept Christian alive.

She went on the kidney transplant list in February but told few people about her illness. Still, it was hard for friends not to notice that something was wrong.

"She is a very private person," Molin said, "and she didn't want anyone to know, but she told me she needed a kidney transplant. And I said, 'Lori, why didn't you tell me? I would give you a kidney.'"

Christian was reluctant to ask that of her friend and, in fact, hated even asking her family to be tested for blood and organ compatibility. But of six people who were screened, two were matches, including Molin and Christian's sister-in-law. Molin was insistent.

sarah.avery@newsobserver.com or 919-829-4882

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