Men and women in their mid-40s on average had no heart disease or diabetes when the study began. They were followed for an average of 32 years.
A total of 1,594 heart disease deaths occurred, 31 of them in people who started the study with normal blood pressure and cholesterol.
A total of 1,187 participants -- 494 of them overweight or obese -- had normal blood pressure (120 over 80 or lower) and cholesterol levels (under 200) at the outset.
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